Surface-Functionalised Copper Oxide Nanoparticles: A Pathway to Multidrug-Resistant Pathogen Control in Medical Devices

James Hall, Subbareddy Mekapothula, Rebecca Coxhill, Dominic Craske, Adam M Varney, Gareth W V Cave, Samantha McLean, Eleonore Fröhlich · 2024

Read Surface-Functionalised Copper Oxide Nanoparticles: A Pathway to Multidrug-Resistant Pathogen Control in Medical Devices by James Hall, Subbareddy Mekapothula, Rebecca Coxhill, Dominic Craske, Adam M Varney, Gareth W V Cave, Samantha McLean, Eleonore Fröhlich (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11643601.txt.

Description

James Hall and co-authors coat medical silicone tubing with copper oxide nanoparticles to fight drug-resistant germs on devices. Antibiotic resistance makes device infections a growing danger. Their 2024 study coats the particles with an amino acid, then bonds them to medical-grade silicone with a linking agent.

The coating killed both major germ classes, including drug-resistant strains, in lab tests. It did not harm human cells, held fast to the tubing, and did not leach. The method can be applied in the factory or added later to existing devices. The authors present it as a flexible way to give medical devices their own germ defense.

Catalog record

CREATORJames Hall, Subbareddy Mekapothula, Rebecca Coxhill, Dominic Craske, Adam M Varney, Gareth W V Cave, Samantha McLean, Eleonore Fröhlich
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11643601

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