Post-Sterilization Physicochemical Characterization and Biological Activity of Cellulose Nanocrystals Coated with PDDA
Ashley Donato, Siddharth Nadkarni, Lakshay Tiwari, Serafina Poran, Rajesh Sunasee, Karina Ckless · 2024
Read Post-Sterilization Physicochemical Characterization and Biological Activity of Cellulose Nanocrystals Coated with PDDA by Ashley Donato, Siddharth Nadkarni, Lakshay Tiwari, Serafina Poran, Rajesh Sunasee, Karina Ckless (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11643580.txt.
Description
Ashley Donato and co-authors check how heat sterilizing changes tiny cellulose crystals coated for medical use. Their 2024 study coats the crystals with a charged polymer in two chain lengths, long and short. Such crystals began in drug delivery and now draw wider medical interest. Once in body fluids, they pick up a coat of proteins that can shift their size, charge, and action. The team tested both coats after autoclave treatment.
Heat changed the coated crystals a lot, most of all with the short coat. The long coat hit cell life and blood fit harder than the short one. Cell immune replies also shifted with whether serum was present, a sign that the protein coat steers how cells read the material.
Catalog record
| CREATOR | Ashley Donato, Siddharth Nadkarni, Lakshay Tiwari, Serafina Poran, Rajesh Sunasee, Karina Ckless |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |