Counteractive Effects of Copper Nanoparticles and Betacellulin on Ovarian Cells
Alexander V. Sirotkin, Paula Romero-Navarro, Barbora Loncová, Zuzana Fabová, Michaela Bartušová, Abdel Halim Harrath, Francisco Alonso · 2024
Read Counteractive Effects of Copper Nanoparticles and Betacellulin on Ovarian Cells by Alexander V. Sirotkin, Paula Romero-Navarro, Barbora Loncová, Zuzana Fabová, Michaela Bartušová, Abdel Halim Harrath, Francisco Alonso (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11643502.txt.
Description
Alexander Sirotkin and co-authors pit copper nanoparticles against a growth factor in ovarian cells. Their 2024 study cultures pig granulosa cells with each agent alone and both together. Copper particles are known to disturb ovary function, while betacellulin supports cell growth.
The particles entered the cells, cut every growth marker, raised every death marker, and boosted hormone release. The growth factor did the reverse on nearly every count. Added together, the factor blocked and even undid the particles' harm, while the particles blunted the factor's gains. The authors see a direct toxic effect of copper particles. They also see a protective role for the factor.
Catalog record
| CREATOR | Alexander V. Sirotkin, Paula Romero-Navarro, Barbora Loncová, Zuzana Fabová, Michaela Bartušová, Abdel Halim Harrath, Francisco Alonso |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |