Colon mucosal proteomics of ankylosing spondylitis versus gut inflammation
Miao Cheng, Siqi Xiao, Shaer Kayi, Yujie Guan, Yingxin Liu, Jianmei Chen, Hua Chen, Lei Wang, Xiaojin He, Sayed Haidar Abbas Raza, Sayed Haidar Abbas Raza, Sayed Haidar Abbas Raza · 2024
Read Colon mucosal proteomics of ankylosing spondylitis versus gut inflammation by Miao Cheng, Siqi Xiao, Shaer Kayi, Yujie Guan, Yingxin Liu, Jianmei Chen, Hua Chen, Lei Wang, Xiaojin He, Sayed Haidar Abbas Raza, Sayed Haidar Abbas Raza, Sayed Haidar Abbas Raza (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11642932.txt.
Description
Miao Cheng and colleagues compare colon tissue proteins across four groups: healthy people, gut inflammation alone, ankylosing spondylitis alone, and both together. The spine disease often comes with quiet gut inflammation, and shared protein shifts may explain the link. Twenty samples, five per group, were profiled by mass spectrometry, and one protein, NMRAL1, was tested in mouse macrophages.
Each group pairing showed dozens of shifted proteins, from forty-five to over one hundred. The NMRAL1 work in cells probed how it shapes inflammatory signals such as TNF and interleukins after toxin challenge. The dataset gives a base for tracing how gut and spine inflammation overlap at the protein level.
Catalog record
| CREATOR | Miao Cheng, Siqi Xiao, Shaer Kayi, Yujie Guan, Yingxin Liu, Jianmei Chen, Hua Chen, Lei Wang, Xiaojin He, Sayed Haidar Abbas Raza, Sayed Haidar Abbas Raza, Sayed Haidar Abbas Raza |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |