Combined Therapy with Azathioprine, Prednisone, and Enalapril in Children with IgAN and IgAVN
Małgorzata Mizerska-Wasiak, Miłosz Starczyński, Wojciech Wasiak, Jadwiga Małdyk, Emilia Płatos, Małgorzata Pańczyk-Tomaszewska, Hiroshi Tanaka · 2024
Read Combined Therapy with Azathioprine, Prednisone, and Enalapril in Children with IgAN and IgAVN by Małgorzata Mizerska-Wasiak, Miłosz Starczyński, Wojciech Wasiak, Jadwiga Małdyk, Emilia Płatos, Małgorzata Pańczyk-Tomaszewska, Hiroshi Tanaka (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11642697.txt.
Description
Małgorzata Mizerska-Wasiak and co-authors evaluate, in twenty twenty-four, a triple drug therapy for children with two related kidney diseases, IgA nephropathy and IgA vasculitis nephritis. Both deposit an antibody in the kidneys and cause blood and protein in urine. Sixty-eight children diagnosed by biopsy took part. Thirty-six got the triple therapy: azathioprine, prednisone, and enalapril, for one year, with a control biopsy. Thirty-two controls got enalapril alone. After a year, the triple therapy group showed a significant drop in proteinuria, cleared in nearly all, and in hematuria.
Proteinuria fell far more in the treated group than in controls, for both diseases. Biopsy scores for two damage features improved often in the treated group. The authors discuss which children need the stronger therapy.
Catalog record
| CREATOR | Małgorzata Mizerska-Wasiak, Miłosz Starczyński, Wojciech Wasiak, Jadwiga Małdyk, Emilia Płatos, Małgorzata Pańczyk-Tomaszewska, Hiroshi Tanaka |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |