Global and Regional Sex-Related Differences, Asymmetry, and Peak Age of Brain Myelination in Healthy Adults

Marina Y. Khodanovich, Mikhail V. Svetlik, Anna V. Naumova, Anna V. Usova, Valentina Y. Pashkevich, Marina V. Moshkina, Maria M. Shadrina, Daria A. Kamaeva, Victoria B. Obukhovskaya, Nadezhda G. Kataeva, Anastasia Y. Levina, Yana A. Tumentceva, Vasily L. Yarnykh · 2024

Read Global and Regional Sex-Related Differences, Asymmetry, and Peak Age of Brain Myelination in Healthy Adults by Marina Y. Khodanovich, Mikhail V. Svetlik, Anna V. Naumova, Anna V. Usova, Valentina Y. Pashkevich, Marina V. Moshkina, Maria M. Shadrina, Daria A. Kamaeva, Victoria B. Obukhovskaya, Nadezhda G. Kataeva, Anastasia Y. Levina, Yana A. Tumentceva, Vasily L. Yarnykh (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11642669.txt.

Description

Led by Marina Y. Khodanovich, a team of thirteen researchers measured how brain myelination differs by sex and hemisphere in healthy adults. Myelin insulates nerve fibers, and its normal adult pattern is still poorly understood. The twenty twenty-four study scanned forty-two adults aged nineteen to sixty-seven. Nineteen were men and twenty-three were women. A fast MRI method mapped the macromolecular proton fraction, an index of myelin content.

Men showed higher myelination than women in global white matter, most fiber tracts, and the putamen. The largest gaps, over four percent, appeared in frontal white matter and several fiber bundles. Hemisphere asymmetries were mostly shared between sexes, though some regions were sex-specific. Most regions also showed age peaks, charting when myelination tops out across the adult brain.

Catalog record

CREATORMarina Y. Khodanovich, Mikhail V. Svetlik, Anna V. Naumova, Anna V. Usova, Valentina Y. Pashkevich, Marina V. Moshkina, Maria M. Shadrina, Daria A. Kamaeva, Victoria B. Obukhovskaya, Nadezhda G. Kataeva, Anastasia Y. Levina, Yana A. Tumentceva, Vasily L. Yarnykh
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11642669

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