Dickkopf 3 as a New Monitoring Tool for Kidney Function After Living Kidney Donation
Antonia Schuster, Louisa Steines, Bernhard Banas, Tobias Bergler, Avnesh S Thakor · 2024
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Description
Antonia Schuster and co-authors test a urine protein as an early warning for kidney donors. Living donors give a kidney and live on one, so spotting who may lose function matters. The protein DKK3 is tied to scarring inside the kidney and fast function loss in other settings.
Their 2024 study followed 117 donors seen between July 2022 and June 2023. Donors were split at a urine DKK3 value of 200: 89 below, 28 above. Before donation the groups' kidney function looked the same. Afterward, the high-DKK3 group's function ran clearly worse and fell faster over time. A simple urine test at checkups could flag donors who need closer watching, the authors suggest.
Catalog record
| CREATOR | Antonia Schuster, Louisa Steines, Bernhard Banas, Tobias Bergler, Avnesh S Thakor |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |