Role of Acyl-CoA Thioesterase 7 in Regulating Fatty Acid Metabolism and Its Contribution to the Onset and Progression of Bovine Clinical Mastitis
Bin Zhou, Bohao Zhang, Jiangyuan Han, Junjun Zhang, Jianfu Li, Weitao Dong, Xingxu Zhao, Yong Zhang, Quanwei Zhang, Margherita Maffei, Gaia Scabia · 2024
Read Role of Acyl-CoA Thioesterase 7 in Regulating Fatty Acid Metabolism and Its Contribution to the Onset and Progression of Bovine Clinical Mastitis by Bin Zhou, Bohao Zhang, Jiangyuan Han, Junjun Zhang, Jianfu Li, Weitao Dong, Xingxu Zhao, Yong Zhang, Quanwei Zhang, Margherita Maffei, Gaia Scabia (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11642332.txt.
Description
Bin Zhou and co-authors present a 2024 study of a fat-processing enzyme in dairy cow mastitis. Clinical mastitis, an inflammation of the udder, is common and costly in dairy herds. Fatty acid handling in the gland may feed the disease, but the links were murky.
The team mined an earlier protein survey of cow tissue for terms and pathways tied to fatty acid work. One enzyme stood out among the candidates: acyl-CoA thioesterase 7, shortened to ACOT7. Stains placed it mainly in the fluid of the gland's epithelial cells. In sick glands, both its gene message and protein ran higher than in healthy ones. The authors connect the enzyme to the lengthening of long-chain fats and the making of unsaturated fats. It may serve as a marker or target in this disease.
Catalog record
| CREATOR | Bin Zhou, Bohao Zhang, Jiangyuan Han, Junjun Zhang, Jianfu Li, Weitao Dong, Xingxu Zhao, Yong Zhang, Quanwei Zhang, Margherita Maffei, Gaia Scabia |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |