Fibroblast Heterogeneity in Inflammatory Bowel Disease
Bo-Jun Ke, Gabriele Dragoni, Gianluca Matteoli · 2024
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Description
Bo-Jun Ke, Gabriele Dragoni, and Gianluca Matteoli review the varied roles of fibroblast cells in inflammatory bowel disease in a 2024 paper. Fibroblasts help keep gut tissue in balance and guide repair after injury. In bowel diseases such as Crohn disease and ulcerative colitis, they also send signals that feed swelling, shape immune cell behavior, and drive scarring.
When fibroblast work goes off track, scar based narrowing and blockage of the gut can follow, a common problem in late disease. The review stresses that fibroblasts are not one uniform kind of cell. Mapping their subtypes and shifting roles could open precise treatments that cut both swelling and scarring.
Catalog record
| CREATOR | Bo-Jun Ke, Gabriele Dragoni, Gianluca Matteoli |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |