Anemia and Mineral Bone Disorder in Kidney Disease Patients: The Role of FGF-23 and Other Related Factors
Nazareno Carullo, David Sorbo, Teresa Faga, Sara Pugliese, Maria Teresa Zicarelli, Davide Costa, Nicola Ielapi, Yuri Battaglia, Antonio Pisani, Giuseppe Coppolino, Davide Bolignano, Ashour Michael, Raffaele Serra, Michele Andreucci, Christy C Bridges · 2024
Read Anemia and Mineral Bone Disorder in Kidney Disease Patients: The Role of FGF-23 and Other Related Factors by Nazareno Carullo, David Sorbo, Teresa Faga, Sara Pugliese, Maria Teresa Zicarelli, Davide Costa, Nicola Ielapi, Yuri Battaglia, Antonio Pisani, Giuseppe Coppolino, Davide Bolignano, Ashour Michael, Raffaele Serra, Michele Andreucci, Christy C Bridges (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641783.txt.
Description
Nazareno Carullo and co-authors review how anemia and bone disorder intertwine in kidney disease. Their 2024 paper centers on two signals: erythropoietin, which drives red cell making, and FGF-23, which keeps blood phosphate in range. Both go astray as kidneys fail. The review lays out how each is regulated and how they act.
The pair also talk to each other, and to partners like Klotho, vitamin D, and iron stores. FGF-23 may feed anemia and inflammation beyond its phosphate job. The authors sketch a kidney, marrow, and bone axis that drives the joint disorder. Grasping these links could sharpen treatment of two of the harshest burdens in chronic kidney disease.
Catalog record
| CREATOR | Nazareno Carullo, David Sorbo, Teresa Faga, Sara Pugliese, Maria Teresa Zicarelli, Davide Costa, Nicola Ielapi, Yuri Battaglia, Antonio Pisani, Giuseppe Coppolino, Davide Bolignano, Ashour Michael, Raffaele Serra, Michele Andreucci, Christy C Bridges |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |