Exploring Aerobic Energy Metabolism in Breast Cancer: A Mutational Profile of Glycolysis and Oxidative Phosphorylation
Ricardo Cunha de Oliveira, Giovanna C. Cavalcante, Giordano B. Soares-Souza · 2024
Read Exploring Aerobic Energy Metabolism in Breast Cancer: A Mutational Profile of Glycolysis and Oxidative Phosphorylation by Ricardo Cunha de Oliveira, Giovanna C. Cavalcante, Giordano B. Soares-Souza (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641591.txt.
Description
Ricardo Cunha de Oliveira and two co-authors scan breast cancer genomes for faults in energy genes, in a 2024 paper. Breast cancer is the tumor that strikes women most worldwide, and how its cells burn fuel helps drive its spread. The team read the gene records of 968 patients from a big cancer atlas, focusing on 205 genes tied to two fuel paths: sugar burning and oxygen-based burning.
They found 408 faults spread over 132 of those genes. Some faulty genes are known drivers in other cancers, and the set tied into famous breast cancer genes as well. Seven faults stood out for strong signs of harm and past links to disease. The authors flag those as leads for future tests that could guide care.
Catalog record
| CREATOR | Ricardo Cunha de Oliveira, Giovanna C. Cavalcante, Giordano B. Soares-Souza |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |