The Aggravating Role of Failing Neuropeptide Networks in the Development of Sporadic Alzheimer’s Disease
Miklós Jászberényi, Balázs Thurzó, Arumugam R Jayakumar, Andrew V Schally, Katalin Prokai-Tatrai · 2024
Read The Aggravating Role of Failing Neuropeptide Networks in the Development of Sporadic Alzheimer’s Disease by Miklós Jászberényi, Balázs Thurzó, Arumugam R Jayakumar, Andrew V Schally, Katalin Prokai-Tatrai (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641508.txt.
Description
Miklós Jászberényi and co-authors argue that failing brain messengers hasten Alzheimer disease in this 2024 review. The common sporadic form may be aging of the brain sped up, with stubborn amyloid piling as clearance fades. The authors survey the neuropeptide families their own work has long studied. Orexins, ghrelin, apelin, and several hormone-releasing systems all appear.
Each network normally tunes sleep, appetite, stress, and memory circuits. As these regulators falter, the brain's housekeeping and rhythms slip further. The review closes with the drug outlook: blockers and boosters of these peptide systems as candidate tools to slow the disease's advance.
Catalog record
| CREATOR | Miklós Jászberényi, Balázs Thurzó, Arumugam R Jayakumar, Andrew V Schally, Katalin Prokai-Tatrai |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 102 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |