Increased Leptin Levels in Plasma and Serum in Patients with Metabolic Disorders: A Systematic Review and Meta-Analysis
Yazmín Hernández-Díaz, María de los Ángeles Ovando-Almeida, Ana Fresán, Isela Esther Juárez-Rojop, Alma Delia Genis-Mendoza, Humberto Nicolini, Thelma Beatriz González-Castro, Carlos Alfonso Tovilla-Zárate, María Lilia López-Narváez · 2024
Read Increased Leptin Levels in Plasma and Serum in Patients with Metabolic Disorders: A Systematic Review and Meta-Analysis by Yazmín Hernández-Díaz, María de los Ángeles Ovando-Almeida, Ana Fresán, Isela Esther Juárez-Rojop, Alma Delia Genis-Mendoza, Humberto Nicolini, Thelma Beatriz González-Castro, Carlos Alfonso Tovilla-Zárate, María Lilia López-Narváez (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641391.txt.
Description
Yazmín Hernández-Díaz and co-authors pooled in 2024 the evidence on leptin levels in people with metabolic disorders. Leptin is a hormone tied to appetite and fat stores. Studies had linked it to diabetes and obesity, but results clashed and no consensus existed. The team searched major databases and combined fifteen reports covering 1,388 cases and 3,536 controls.
People with diabetes showed clearly higher leptin in both serum and plasma than controls. The pattern held across sex and population groups. People with obesity also had much higher serum leptin. The authors argue for watching leptin levels in these patients. They caution that broader and more careful studies are still needed before firm conclusions stick. The work gives clinicians a firmer summary of a contested marker.
Catalog record
| CREATOR | Yazmín Hernández-Díaz, María de los Ángeles Ovando-Almeida, Ana Fresán, Isela Esther Juárez-Rojop, Alma Delia Genis-Mendoza, Humberto Nicolini, Thelma Beatriz González-Castro, Carlos Alfonso Tovilla-Zárate, María Lilia López-Narváez |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |