High Absorption and Elasticity of a Novel Transgenic Silk with Egg Case Silk Protein from Nephila clavata

Yichen Wang, Yuhang Lin, Yongkang Luo, Di Zeng, Haibo He, Tianfu Zhao, Naozumi Teramoto · 2024

Read High Absorption and Elasticity of a Novel Transgenic Silk with Egg Case Silk Protein from Nephila clavata by Yichen Wang, Yuhang Lin, Yongkang Luo, Di Zeng, Haibo He, Tianfu Zhao, Naozumi Teramoto (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641369.txt.

Description

Yichen Wang and six colleagues engineer silkworms to spin silk containing spider egg case protein. Spider egg case silk is hard, water-resistant, and highly moisture absorbent, but spiders cannot be farmed at scale. Silkworms share a similar spinning system, making them ideal bioreactors for spider proteins.

Using a piggyBac transposon system, the team inserted the egg case silk gene from the spider Nephila clavata into the silkworm's heavy-chain expression system. The silk glands produced a new transgenic silk with significantly higher initial modulus and moisture absorption. The authors present the result as a reference for large-scale production of spider egg case proteins, with prospects for environmentally friendly fiber materials.

Catalog record

CREATORYichen Wang, Yuhang Lin, Yongkang Luo, Di Zeng, Haibo He, Tianfu Zhao, Naozumi Teramoto
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11641369

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