Exposure of Primary Human Skin Fibroblasts to Carbon Dioxide-Containing Solution Significantly Reduces TGF-β-Induced Myofibroblast Differentiation In Vitro

Maxine Fleckner, Niklas K Döhmen, Katharina Salz, Till Christophers, Joachim Windolf, Christoph V Suschek, Lisa Oezel, Giulio Gabbiani · 2024

Read Exposure of Primary Human Skin Fibroblasts to Carbon Dioxide-Containing Solution Significantly Reduces TGF-β-Induced Myofibroblast Differentiation In Vitro by Maxine Fleckner, Niklas K Döhmen, Katharina Salz, Till Christophers, Joachim Windolf, Christoph V Suschek, Lisa Oezel, Giulio Gabbiani (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641328.txt.

Description

Maxine Fleckner and co-authors bathe human skin cells in carbon dioxide fluid to see if scar-type change can be curbed, in a study from two thousand twenty-four. A growth signal that pushes cells toward scar form drove the test. Life, growth, and drift of the cells were all checked.

An hour of the gas left cells alive and moving as before. Yet the scar marker protein fell sharply, more with longer and stronger doses. Cell energy making dropped in step, by a route not shared with a nitrogen control. The team reads the gas as a brake on scar change via energy. Readers get a fresh lead against thick scars and keloids.

Catalog record

CREATORMaxine Fleckner, Niklas K Döhmen, Katharina Salz, Till Christophers, Joachim Windolf, Christoph V Suschek, Lisa Oezel, Giulio Gabbiani
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE60 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11641328

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