Single Nucleotide Polymorphisms on Toll-like Receptor-4 and the Risk of Developing Skin Cancer
Nabiha Yusuf, Noha Sharafeldin, Mohammad Saleem, Tom Callens, Ludwine M Messiaen, Craig A Elmets, Silvia Cantara · 2024
Read Single Nucleotide Polymorphisms on Toll-like Receptor-4 and the Risk of Developing Skin Cancer by Nabiha Yusuf, Noha Sharafeldin, Mohammad Saleem, Tom Callens, Ludwine M Messiaen, Craig A Elmets, Silvia Cantara (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641301.txt.
Description
Nabiha Yusuf and co-authors test whether variants in an immune gene affect skin cancer risk in a 2024 study. Sunlight is a known risk for skin cancer, and the gene TLR4 shapes immune response to sun damage in mice. Variants in it raise or lower risk for cancers in other organs.
Patients and controls at an Alabama center gave blood for genotyping and answered surveys on sun habits and family history. The study focused on keratinocyte carcinomas, the most common skin cancers. Little was known about this gene in human skin cancer before. Results add a genetic piece to a puzzle dominated by sun exposure.
Catalog record
| CREATOR | Nabiha Yusuf, Noha Sharafeldin, Mohammad Saleem, Tom Callens, Ludwine M Messiaen, Craig A Elmets, Silvia Cantara |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |