Sex-Related Differences in Pancreatic Ductal Adenocarcinoma Progression and Response to Therapy
Jelena Grahovac, Ana Đurić, Miljana Tanić, Ana Krivokuća · 2024
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Description
Jelena Grahovac and co-authors reviewed in 2024 how biological sex shapes pancreatic cancer, one of the deadliest cancers. Sex affects how often the disease strikes, how it grows, and how it responds to treatment, yet trials and lab work often ignore it.
The review covers sex gaps in rates and deaths, in gene and gene control patterns, and in immune attack on the tumor. It also looks at hormones, wasting of the body, and how well therapies work in men versus women. The authors urge researchers to build sex into study design from the start. Doing so, they argue, is a cheap step toward sharper, more personal treatment for this hard disease.
Catalog record
| CREATOR | Jelena Grahovac, Ana Đurić, Miljana Tanić, Ana Krivokuća |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |