The Phytochemical Profile of the Petroleum Ether Extract of Purslane Leaves and Its Anticancer Effect on 4-(Methylnitrosamino)-1-(3-pyridyl)-1-buta-4 None (NNK)-Induced Lung Cancer in Rats
Asmaa S Abd Elkarim, Safaa H Mohamed, Naglaa A Ali, Ghada H Elsayed, Mohamed S Aly, Abdelbaset M Elgamal, Wael M Elsayed, Samah A El-Newary, Aaron C Tan · 2024
Read The Phytochemical Profile of the Petroleum Ether Extract of Purslane Leaves and Its Anticancer Effect on 4-(Methylnitrosamino)-1-(3-pyridyl)-1-buta-4 None (NNK)-Induced Lung Cancer in Rats by Asmaa S Abd Elkarim, Safaa H Mohamed, Naglaa A Ali, Ghada H Elsayed, Mohamed S Aly, Abdelbaset M Elgamal, Wael M Elsayed, Samah A El-Newary, Aaron C Tan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641252.txt.
Description
Asmaa Abd Elkarim and co-authors test a purslane leaf extract against lung cancer in rats, in a 2024 paper. The cancer was triggered by NNK, a tobacco-linked chemical. In dishes, the extract killed lung cancer cells nearly as well as a standard chemotherapy drug. The team then dosed rats by mouth for twenty weeks.
Treated rats showed a clear recovery pattern with a good safety margin. A key cancer marker in the lung fell, growth signals dropped, blood-vessel and inflammation drivers eased, and a death-promoting switch rose sharply. Antioxidant defenses recovered while oxidative stress fell. Tissue slices confirmed the improvement. The authors present purslane as a multi-pronged candidate worth further study.
Catalog record
| CREATOR | Asmaa S Abd Elkarim, Safaa H Mohamed, Naglaa A Ali, Ghada H Elsayed, Mohamed S Aly, Abdelbaset M Elgamal, Wael M Elsayed, Samah A El-Newary, Aaron C Tan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 88 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |