Highly Efficient Methods with a Generalized Linear Mixed Model for the Quantitative Trait Locus Mapping of Resistance to Columnaris Disease in Rainbow Trout (Oncorhynchus mykiss)
Yuxin Song, Zhongyu Chang, Ao Chen, Yunfeng Zhao, Yanliang Jiang, Li Jiang, Alberto Cuesta · 2024
Read Highly Efficient Methods with a Generalized Linear Mixed Model for the Quantitative Trait Locus Mapping of Resistance to Columnaris Disease in Rainbow Trout (Oncorhynchus mykiss) by Yuxin Song, Zhongyu Chang, Ao Chen, Yunfeng Zhao, Yanliang Jiang, Li Jiang, Alberto Cuesta (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641235.txt.
Description
Yuxin Song and co-authors compared fast gene-scan methods for disease resistance in rainbow trout in 2024. The disease, columnaris, harms farmed trout. Standard mixed models failed to control false hits for this trait, so the team tested three generalized tools on the same fish data.
Scans covered nearly twenty-six thousand DNA markers. The fastest tool found seven linked markers, while the other two found four and three. Together they explained about nine percent of trait variation. Heritability came out far higher than an earlier estimate, at 0.71 rather than 0.35. Three nearby genes and one further gene now guide marker-based breeding.
Catalog record
| CREATOR | Yuxin Song, Zhongyu Chang, Ao Chen, Yunfeng Zhao, Yanliang Jiang, Li Jiang, Alberto Cuesta |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |