Evaluation of the Anti-Cancer Potential of Extracellular Vesicles Derived from Human Amniotic Fluid Stem Cells: Focus on Effective miRNAs in the Treatment of Melanoma Progression

Martina Gatti, Francesca Beretti, Gloria Ravegnini, Francesca Gorini, Eleonora Ceneri, Emma Bertucci, Matilde Y. Follo, Tullia Maraldi · 2024

Read Evaluation of the Anti-Cancer Potential of Extracellular Vesicles Derived from Human Amniotic Fluid Stem Cells: Focus on Effective miRNAs in the Treatment of Melanoma Progression by Martina Gatti, Francesca Beretti, Gloria Ravegnini, Francesca Gorini, Eleonora Ceneri, Emma Bertucci, Matilde Y. Follo, Tullia Maraldi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11641077.txt.

Description

Martina Gatti and co-authors test whether fluid born stem cells can fight melanoma in a 2024 study. Stem cells from amniotic fluid are easy to gather with few ethical snags, and they shed tiny parcels called extracellular vesicles. Those parcels carry proteins and small RNA strands that may slow cancer growth.

Profiling showed the parcels are rich in factors tied to antioxidant and anti cancer effects. When melanoma cells met the parcels, fewer cells reached a key growth phase, more cells died by the apoptosis path, and spread and invasion fell. The team reads this as proof that such parcels can curb melanoma growth in the lab.

Catalog record

CREATORMartina Gatti, Francesca Beretti, Gloria Ravegnini, Francesca Gorini, Eleonora Ceneri, Emma Bertucci, Matilde Y. Follo, Tullia Maraldi
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE51 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11641077

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