Efficacy and Safety of Useul for Dry Eye Disease: Protocol for a Randomized, Double-Blind, Placebo-Controlled, Parallel, Phase 2 Clinical Trial
Yee-Ran Lyu, O-Jin Kwon, Bongkyun Park, Hyun-A Jung, Ga-Young Lee, Chan-Sik Kim, Pinakin Gunvant Davey, Andrzej Grzybowski · 2024
Read Efficacy and Safety of Useul for Dry Eye Disease: Protocol for a Randomized, Double-Blind, Placebo-Controlled, Parallel, Phase 2 Clinical Trial by Yee-Ran Lyu, O-Jin Kwon, Bongkyun Park, Hyun-A Jung, Ga-Young Lee, Chan-Sik Kim, Pinakin Gunvant Davey, Andrzej Grzybowski (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11640859.txt.
Description
Yee-Ran Lyu and co-authors set out a trial protocol for a plant extract in dry eye disease in this 2024 paper. Dry eye is very common and a growing public health burden. Current treatments can cause side effects or fall short, so a safe and effective option is still needed.
The planned phase 2 trial will enroll 120 patients at a Korean medicine hospital in Daejeon. Patients will get a standard dose, a high dose, or a placebo, twice a day for 12 weeks, with five clinic visits. The extract, from a plant root, is expected to raise tear flow and calm eye surface swelling. Eye tests, symptom scores, and safety checks will judge the outcome.
Catalog record
| CREATOR | Yee-Ran Lyu, O-Jin Kwon, Bongkyun Park, Hyun-A Jung, Ga-Young Lee, Chan-Sik Kim, Pinakin Gunvant Davey, Andrzej Grzybowski |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |