Advances in Induced Pluripotent Stem Cell-Derived Natural Killer Cell Therapy
Wenhua Qiao, Peng Dong, Hui Chen, Jianmin Zhang, Ira-Ida Skvortsova · 2024
Read Advances in Induced Pluripotent Stem Cell-Derived Natural Killer Cell Therapy by Wenhua Qiao, Peng Dong, Hui Chen, Jianmin Zhang, Ira-Ida Skvortsova (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11640743.txt.
Description
Wenhua Qiao and co-authors review a new way to make cancer-fighting immune cells in the lab, in work published in 2024. The cells are natural killer cells, a type that can kill virus-infected and cancer cells. Instead of taking them from donors, labs can grow them from induced pluripotent stem cells, which are adult cells reset to a flexible state.
The review covers the steps used to turn those stem cells into killer cells at a scale fit for clinics. It also covers gene edits that help the cells find tumors, grow well, and last longer in the body. The authors weigh the limits of older cell sources, such as donor cells that grow poorly. They close with the problems still to solve before such therapy is routine.
Catalog record
| CREATOR | Wenhua Qiao, Peng Dong, Hui Chen, Jianmin Zhang, Ira-Ida Skvortsova |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |