Metabolic Adaptations in Cancer and the Host Using Drosophila Models and Advanced Tools
Ernesto Saez-Carrion, Mario Aguilar-Aragon, Lucia García-López, Maria Dominguez, Mary Luz Uribe · 2024
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Description
Ernesto Saez-Carrion and colleagues review how cancers reshape metabolism in fruit fly models, in work published in 2024. Tumours must draw nutrients from nearby and distant tissues without killing the host too fast. Food supply is limited, so tumour and host choices are tightly linked in this balance.
The review argues that the fruit fly offers a clean system to untangle those links. Levels run from single tumour cells to whole body markers of change. New high throughput tools and diet based tests deepen what can be measured in the model. Readers see how tumours adapt under varied food and tissue settings. The authors link those lessons to fresh ideas for therapy design.
Catalog record
| CREATOR | Ernesto Saez-Carrion, Mario Aguilar-Aragon, Lucia García-López, Maria Dominguez, Mary Luz Uribe |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 73 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |