Painful Diabetic Neuropathy: Sex-Specific Mechanisms and Differences from Animal Models to Clinical Outcomes
Emma Merlin, Chiara Salio, Francesco Ferrini, Michel Baudry · 2024
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Description
Emma Merlin and co-authors wrote this 2024 review on painful nerve damage caused by diabetes. High blood sugar can harm nerves over time, and in many patients the harm brings lasting pain. No current therapy stops the pain or slows the disease well, and the root causes stay partly unclear.
The review pulls together evidence that pain pathways differ between the sexes. It compares findings from animal models with data from human patients, stage by stage. Differences show up in how the disease unfolds and how it presents in the clinic. The authors argue that naming these sex-specific paths could guide sharper treatments. Better animal models, matched to human data, are part of that plan.
Catalog record
| CREATOR | Emma Merlin, Chiara Salio, Francesco Ferrini, Michel Baudry |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |