Preclinical Photodynamic Therapy Targeting Blood Vessels with AGuIX® Theranostic Nanoparticles
Ewa Kowolik, Dariusz Szczygieł, Małgorzata Szczygieł, Agnieszka Drzał, Kalyani Vemuri, Anna-Karin Olsson, Arjan W. Griffioen, Patrycja Nowak-Sliwinska, Agnieszka Wolnicka-Glubisz, Martyna Elas · 2024
Read Preclinical Photodynamic Therapy Targeting Blood Vessels with AGuIX® Theranostic Nanoparticles by Ewa Kowolik, Dariusz Szczygieł, Małgorzata Szczygieł, Agnieszka Drzał, Kalyani Vemuri, Anna-Karin Olsson, Arjan W. Griffioen, Patrycja Nowak-Sliwinska, Agnieszka Wolnicka-Glubisz, Martyna Elas (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11640380.txt.
Description
Ewa Kowolik and co-authors test light based therapy with tiny particles against a grave brain tumor in 2024. The tumor is the most common aggressive brain cancer in adults. Light therapy uses a drug that wakes under light and kills cells. The particles carry such a drug and also aid imaging. The team targets tumor blood vessels.
Tests ran in cell layers, cell balls, and tumors in eggs and mice. The therapy killed both vessel cells and tumor cells in dishes. It curbed ball growth and wrecked tumor vessels in eggs. In mice, vessels were harmed and oxygen fell a bit. Effect strength in mice hinged on how many vessels the tumor had at the start.
Catalog record
| CREATOR | Ewa Kowolik, Dariusz Szczygieł, Małgorzata Szczygieł, Agnieszka Drzał, Kalyani Vemuri, Anna-Karin Olsson, Arjan W. Griffioen, Patrycja Nowak-Sliwinska, Agnieszka Wolnicka-Glubisz, Martyna Elas |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |