FoxP3+ Regulatory T-Cell Quantities in Nodal T-Follicular Helper Cell Lymphomas and Peripheral T-Cell Lymphomas Not Otherwise Specified and Their Impact on Overall Survival

Eva Erzar, Alexandar Tzankov, Janja Ocvirk, Biljana Grčar Kuzmanov, Lučka Boltežar, Veronika Kloboves Prevodnik, Gorana Gašljević · 2024

Read FoxP3+ Regulatory T-Cell Quantities in Nodal T-Follicular Helper Cell Lymphomas and Peripheral T-Cell Lymphomas Not Otherwise Specified and Their Impact on Overall Survival by Eva Erzar, Alexandar Tzankov, Janja Ocvirk, Biljana Grčar Kuzmanov, Lučka Boltežar, Veronika Kloboves Prevodnik, Gorana Gašljević (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11640135.txt.

Description

Eva Erzar and co-authors count calming regulatory T cells inside two kinds of nodal T-cell lymphoma and ask whether the count tracks survival, in work from 2024. The tumor's immune neighborhood shapes how these cancers grow. Regulatory cells can shield a tumor or restrain it, and their role here was unsettled.

Biopsies from 105 lymphoma cases and seventeen reactive nodes were stained for a marker of the regulatory cells. Scorers tallied the marked cells by eye and tested several cut points against survival. The cells appeared in nearly all samples. Lower counts pointed one way on survival and higher counts another, by subtype. The study sorts where the cells help and where they hurt.

Catalog record

CREATOREva Erzar, Alexandar Tzankov, Janja Ocvirk, Biljana Grčar Kuzmanov, Lučka Boltežar, Veronika Kloboves Prevodnik, Gorana Gašljević
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11640135

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