Hematologic Toxicity Profiles and the Impact of Hemoglobin Nadir and Transfusion on Oncologic Outcome in Definitive Radiochemotherapy for Cervical Cancer
Eva Meixner, Laura Wermes, Line Hoeltgen, Lisa Antonia von Diest, Elisabetta Sandrini, Semi Harrabi, Katharina Seidensaal, Philipp Hoegen-Saßmannshausen, Maria Vinsensia, Laila König, Nathalie Arians, Jürgen Debus, Juliane Hörner-Rieber · 2024
Read Hematologic Toxicity Profiles and the Impact of Hemoglobin Nadir and Transfusion on Oncologic Outcome in Definitive Radiochemotherapy for Cervical Cancer by Eva Meixner, Laura Wermes, Line Hoeltgen, Lisa Antonia von Diest, Elisabetta Sandrini, Semi Harrabi, Katharina Seidensaal, Philipp Hoegen-Saßmannshausen, Maria Vinsensia, Laila König, Nathalie Arians, Jürgen Debus, Juliane Hörner-Rieber (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11640044.txt.
Description
Eva Meixner and a large team review in 2024 the blood side effects of strong treatment for cervical cancer. The standard care mixes radiation with a weekly chemo drug, and newer trials add more drugs at the cost of more blood harm. The team asked what drives that harm and whether it changes outcomes.
They reviewed one hundred forty-seven patients treated over two decades. Severe low white cell counts were rare, and no case reached the most dangerous grade. Hemoglobin, the red cell measure, fell most after the fourth week. Patients whose hemoglobin sank lowest had worse local control of the cancer. Those who needed transfusions also fared worse overall. The authors urge close blood care through the full course.
Catalog record
| CREATOR | Eva Meixner, Laura Wermes, Line Hoeltgen, Lisa Antonia von Diest, Elisabetta Sandrini, Semi Harrabi, Katharina Seidensaal, Philipp Hoegen-Saßmannshausen, Maria Vinsensia, Laila König, Nathalie Arians, Jürgen Debus, Juliane Hörner-Rieber |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |