Circulating Hepcidin Levels Are an Independent Predictor of Survival in Microsatellite Stable Metastatic Colorectal Cancer Patient Candidates for Standard First-Line Treatment
Vincenzo Formica, Antonio Di Grazia, Maria Vittoria Bonomo, Rachele Frascatani, Roberto Mancone, Giovanni Monteleone · 2024
Read Circulating Hepcidin Levels Are an Independent Predictor of Survival in Microsatellite Stable Metastatic Colorectal Cancer Patient Candidates for Standard First-Line Treatment by Vincenzo Formica, Antonio Di Grazia, Maria Vittoria Bonomo, Rachele Frascatani, Roberto Mancone, Giovanni Monteleone (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11639781.txt.
Description
Vincenzo Formica and co-authors test in 2024 whether a blood hormone can forecast survival in advanced bowel cancer. The hormone, hepcidin, steers body iron and is made by bowel tumors in late stages. Their patients all had spread cancer of a stable genetic type and were starting standard first-line drug treatment.
Blood from fifty-five patients and thirty-five healthy volunteers was compared. Patients carried far more of the hormone. Those above a set level had a one-year survival rate of thirty-nine percent against eighty percent below it. The level forecast survival on its own, beyond standard marks, in every patient subgroup.
Catalog record
| CREATOR | Vincenzo Formica, Antonio Di Grazia, Maria Vittoria Bonomo, Rachele Frascatani, Roberto Mancone, Giovanni Monteleone |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |