Structural Characterization and Hypoglycemic Activity of a Glycoprotein Extracted from Auricularia Auricula

Qiping Zhan, Mengdie Yang, Xinqi Zhao, Feifei Liu, Liyan Zhao · 2024

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Description

Qiping Zhan and co-authors extract a sugar-protein from wood ear mushrooms in a 2024 study. Such glycoproteins may help lower blood sugar, but this one's structure and survival through digestion were unknown. The team isolated a fraction called AAG-3 and mapped it fully.

Tests pegged its weight, bond type, amino acid mix, and sheet-like shape under a microscope. A fake digestion run came next, through saliva, stomach, and gut stages. After digestion, the extract blocked two sugar-splitting enzymes more strongly. In insulin-resistant liver cells, it raised sugar uptake and storage and lifted two key enzymes. The authors pitch it as a diet aid candidate for diabetes care.

Catalog record

CREATORQiping Zhan, Mengdie Yang, Xinqi Zhao, Feifei Liu, Liyan Zhao
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11639771

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