Clinical efficacy and safety of organ-sparing cystectomy: a systematic review and meta-analysis

Yi Zhang, Lei Peng, Yang Zhang, Hangxu Li, Songbei Li, Shaohua Zhang, Jianguo Shi · 2024

Read Clinical efficacy and safety of organ-sparing cystectomy: a systematic review and meta-analysis by Yi Zhang, Lei Peng, Yang Zhang, Hangxu Li, Songbei Li, Shaohua Zhang, Jianguo Shi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11639212.txt.

Description

Yi Zhang and co-authors pool the evidence on bladder removal surgery that spares neighboring organs. Their review appeared in 2024. Standard radical surgery for bladder tumors takes nearby organs with the bladder, costing sexual and urinary function. The sparing variant promises to preserve both, but critics fear higher recurrence. Nineteen studies covering 2,057 patients were combined, comparing the two operations on safety, cancer control, and function.

The sparing operation matched the standard one on cancer outcomes in the pooled data while clearly winning on erectile function and continence, day and night. The authors say the fear of extra recurrence was not borne out in these studies. Careful patient selection, they add, is what makes the trade safe.

Catalog record

CREATORYi Zhang, Lei Peng, Yang Zhang, Hangxu Li, Songbei Li, Shaohua Zhang, Jianguo Shi
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11639212

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