REmoval of cytokines during CArdiac surgery (RECCAS): a randomised controlled trial

Andreas Hohn, Nathalie M Malewicz-Oeck, Dirk Buchwald, Thorsten Annecke, Peter K Zahn, Andreas Baumann · 2024

Read REmoval of cytokines during CArdiac surgery (RECCAS): a randomised controlled trial by Andreas Hohn, Nathalie M Malewicz-Oeck, Dirk Buchwald, Thorsten Annecke, Peter K Zahn, Andreas Baumann (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11639119.txt.

Description

Andreas Hohn and co-authors test a blood filter meant to calm inflammation during heart surgery. Their 2024 trial covers the RECCAS study. Bypass machines spark a flood of cytokines that can harm recovery. Thirty-eight older patients were split evenly: half got a sorbent filter during bypass, half standard care.

The main target missed: the lead cytokine level on arrival in intensive care did not differ between groups. Levels on later days matched too. Inside the filter, several cytokines did drop across it during surgery. One heart output measure ran higher in the treated group on day two, and fluid needs fell. Stays, infections, and deaths did not differ. The authors report a neutral trial overall.

Catalog record

CREATORAndreas Hohn, Nathalie M Malewicz-Oeck, Dirk Buchwald, Thorsten Annecke, Peter K Zahn, Andreas Baumann
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE50 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11639119

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