HbA2 levels in children with β-thalassemia trait associated with iron deficiency: A perspective for pediatricians

Şeyda Değermenci, Deniz Aslan · 2024

Read HbA2 levels in children with β-thalassemia trait associated with iron deficiency: A perspective for pediatricians by Şeyda Değermenci, Deniz Aslan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11637608.txt.

Description

Seyda Degermenci and Deniz Aslan study a blood marker in children who carry the beta thalassemia trait in this 2024 paper. Screening relies on hemoglobin A2 level, with 3.5 percent as the cutoff. Iron deficiency can lower that level and hide the trait. Adult studies on this problem disagree, and children had not been studied.

The study covered 213 carrier children. Those with low ferritin counted as iron deficient. Their median A2 level was 4.1 percent, still above the cutoff for most children. Iron sufficient carriers had a higher median of 4.9 percent. Low A2 levels did not track with ferritin level itself. The authors conclude screening still works for most iron deficient carrier children.

Catalog record

CREATORŞeyda Değermenci, Deniz Aslan
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE16 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11637608

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