Genomic epidemiology and immune escape of SARS-CoV-2 recombinant strains circulating in Botswana
Wonderful T. Choga, Irene Gobe, Kedumetse Seru, Dorcas Maruapula, Nokuthula S. Ndlovu, Boitumelo J. L Zuze, Patience Motshosi, Teko Matsuru, Phenyo Sabone, Xiaoyu Yu, Jason T. Blackard, James E. San, Joseph Makhema, Simani Gaseitsiwe, Sikhulile Moyo · 2024
Read Genomic epidemiology and immune escape of SARS-CoV-2 recombinant strains circulating in Botswana by Wonderful T. Choga, Irene Gobe, Kedumetse Seru, Dorcas Maruapula, Nokuthula S. Ndlovu, Boitumelo J. L Zuze, Patience Motshosi, Teko Matsuru, Phenyo Sabone, Xiaoyu Yu, Jason T. Blackard, James E. San, Joseph Makhema, Simani Gaseitsiwe, Sikhulile Moyo (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11636131.txt.
Description
Highlights•There is a low prevalence of circulating SARS-CoV-2 recombinant sequences in Botswana.•XBB* cases were the most predominant SARS-CoV-2 recombinants cases.•We report the first cases of XBJ.1.1 and XM recombinant sequences in Africa.•Most recombinants had breaking points in the receptor-binding domain in spike.•We identified rare mutations of interest, including S:Q474K, that may cause immune escape.
Catalog record
| CREATOR | Wonderful T. Choga, Irene Gobe, Kedumetse Seru, Dorcas Maruapula, Nokuthula S. Ndlovu, Boitumelo J. L Zuze, Patience Motshosi, Teko Matsuru, Phenyo Sabone, Xiaoyu Yu, Jason T. Blackard, James E. San, Joseph Makhema, Simani Gaseitsiwe, Sikhulile Moyo |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |