Reply to: Is there a kindling effect in COPD exacerbations?
David M.G. Halpin, Heath Heatley, David Price · 2024
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Description
Halpin, Heatley, and Price wrote a reply, published in 2024, to comments on their study of flare-ups in a chronic lung disease. The disease, known as COPD, damages the airways and flares in episodes that can land patients in hospital. Their study had asked whether flare-ups before diagnosis predict later ones. Two commentators raised the known point that, in patients already diagnosed and treated, past flare-ups best predict future risk. The reply accepts that point and sharpens what was new.
Their study was the first, they note, in people not yet diagnosed. Even a single flare-up before diagnosis marked higher risk over the next year. More or worse early flare-ups meant still higher risk. Blood cell counts before diagnosis added further signal. The reply argues for acting on that early warning, rather than waiting for the diagnosis to make the risk plain.
Catalog record
| CREATOR | David M.G. Halpin, Heath Heatley, David Price |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |