Prognostic impact of EGFR mutations in T1–4N0M0 lung adenocarcinoma: analyses focus on imaging and pathological features

Jing-Yu Chen, Ying Zhu, Bao-Cong Liu, Hui-Yun Ma, Lu-Jie Li, Mei-Cheng Chen, Shu-Chang Zhou, Xiang-Min Li, Jian-Ting Long, Qiong Li · 2024

Read Prognostic impact of EGFR mutations in T1–4N0M0 lung adenocarcinoma: analyses focus on imaging and pathological features by Jing-Yu Chen, Ying Zhu, Bao-Cong Liu, Hui-Yun Ma, Lu-Jie Li, Mei-Cheng Chen, Shu-Chang Zhou, Xiang-Min Li, Jian-Ting Long, Qiong Li (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11635242.txt.

Description

Jing-Yu Chen and co-authors weigh how a gene mutation shapes outlook in early lung adenocarcinoma, in a 2024 paper. Targeted drugs have lifted survival for advanced cases with the mutation, but its meaning in node free disease was less clear. Four hundred thirty eight patients who had a lobe removed between 2015 and 2016 were sorted by scan and tissue type.

Mutation carriers with part solid nodules stayed free of return longer, while purely solid nodules showed the opposite lean. Low solidity ratios also favored carriers. Across tissue grades the pattern shifted between return free time and total survival. The authors argue that scan and grade context must frame any verdict on the mutation.

Catalog record

CREATORJing-Yu Chen, Ying Zhu, Bao-Cong Liu, Hui-Yun Ma, Lu-Jie Li, Mei-Cheng Chen, Shu-Chang Zhou, Xiang-Min Li, Jian-Ting Long, Qiong Li
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11635242

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