Low-energy extracorporeal shockwave therapy improves locomotor functions, tissue regeneration, and modulating the inflammation induced FGF1 and FGF2 signaling to protect damaged tissue in spinal cord injury of rat model: an experimental animal study

Chieh-Cheng Hsu, Kay LH Wu, Jei-Ming Peng, Yi-No Wu, Hou-Tsung Chen, Meng-Shiou Lee, Jai-Hong Cheng · 2024

Read Low-energy extracorporeal shockwave therapy improves locomotor functions, tissue regeneration, and modulating the inflammation induced FGF1 and FGF2 signaling to protect damaged tissue in spinal cord injury of rat model: an experimental animal study by Chieh-Cheng Hsu, Kay LH Wu, Jei-Ming Peng, Yi-No Wu, Hou-Tsung Chen, Meng-Shiou Lee, Jai-Hong Cheng (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11634128.txt.

Description

Seven authors test low energy shockwave therapy for spinal cord injury in rats in this 2024 study. Spinal cord injury causes severe loss of movement, and current options are few, while shockwave therapy is a noninvasive method already used for muscle and nerve problems.

Rats got either one or three sessions of the therapy, and the team measured walking, gait, tissue state, and inflammation. Three sessions did best by a clear margin: movement scores and run patterns improved, tissue regrowth rose, and inflammation markers fell. Effects on two growth factor signals, FGF1 and FGF2, are part of the story the authors tell. Dose matters, the study suggests.

Catalog record

CREATORChieh-Cheng Hsu, Kay LH Wu, Jei-Ming Peng, Yi-No Wu, Hou-Tsung Chen, Meng-Shiou Lee, Jai-Hong Cheng
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11634128

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