Tumor Heterogeneity of STEAP4 in Malignant Progression of Oral Squamous Cell Carcinoma
Zheng Wu, Wen-Jia Chen, Yang-Zheng Lan, Ze-Xuan Fang, Yan-Yu Hou, Xin-Ning Yu, Hua-Tao Wu, Jing Liu · 2024
Read Tumor Heterogeneity of STEAP4 in Malignant Progression of Oral Squamous Cell Carcinoma by Zheng Wu, Wen-Jia Chen, Yang-Zheng Lan, Ze-Xuan Fang, Yan-Yu Hou, Xin-Ning Yu, Hua-Tao Wu, Jing Liu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11632996.txt.
Description
Zheng Wu and seven co-authors study in 2024 the uneven role of STEAP4, a metal-handling protein, in mouth cancer spread. The protein matters in several gut cancers, yet its place in oral squamous cell carcinoma was unclear. Uneven behavior across tumor types can mislead drug plans.
Stain tests on tumor and normal tissue show low STEAP4 levels in head and neck cancers. Public data tools map its levels, outcome links, and pathways. Head and neck patients with low levels fare favorably overall, while mouth cancer patients fare poorly. No gene changes appear in mouth tumors, while amplification shows in the wider head group. The split marks STEAP4 as a risk factor with tumor-specific behavior.
Catalog record
| CREATOR | Zheng Wu, Wen-Jia Chen, Yang-Zheng Lan, Ze-Xuan Fang, Yan-Yu Hou, Xin-Ning Yu, Hua-Tao Wu, Jing Liu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |