Gene Expression Profiling of Pancreatic Ductal Adenocarcinoma Arising From Intraductal Papillary Mucinous Neoplasms of the Pancreas

William A. Ziaziaris, Christopher S. H. Lim, Loretta Sioson, Anthony J. Gill, Jaswinder S. Samra, Sumit Sahni, Anubhav Mittal · 2024

Read Gene Expression Profiling of Pancreatic Ductal Adenocarcinoma Arising From Intraductal Papillary Mucinous Neoplasms of the Pancreas by William A. Ziaziaris, Christopher S. H. Lim, Loretta Sioson, Anthony J. Gill, Jaswinder S. Samra, Sumit Sahni, Anubhav Mittal (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11632396.txt.

Description

Seven researchers report a study from two thousand twenty-four on how a pancreatic growth turns into cancer. The growths, called IPMNs, form inside the ducts of the pancreas and can step slowly from harmless to malignant. That slow path gives doctors a rare chance to act before cancer forms.

The team took tissue from twelve patients whose growths had already turned into pancreatic cancer. They measured gene activity in cancerous tissue and in tissue that had not yet turned. One hundred fifty-nine genes differed clearly between the two. Pathway analysis then showed which cell programs shift as the growth becomes invasive.

Catalog record

CREATORWilliam A. Ziaziaris, Christopher S. H. Lim, Loretta Sioson, Anthony J. Gill, Jaswinder S. Samra, Sumit Sahni, Anubhav Mittal
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE21 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11632396

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