Efficacy and safety of 4‐hydroxy 2‐methyl‐N‐(5‐methyl‐2‐thiazolyl)‐2H‐1, 2‐benzothiazin‐3‐carboxamide 1,1‐dioxide, a fast‐acting meloxicam formulation, on moderate‐to‐severe pain following abdominal surgery: A phase III randomized controlled trial
Xiaohua Liu, Yanhua Zhao, Mengchang Yang, Jinghua Ren, Wen Ouyang, Saiying Wang, Yufei Shen, Yuanli Gao, Ling Zhao, Zhong Qin, Jun Cao, Jiangyan Xia, Hongmei Zhou, Haihua Zeng, Jiangang Li, Qiongcan Li, Haitao Jiang, Ruiren Zhou, Kaiming Yuan, Shu’an Jin, Xuanqiang Zhang, Chunhui Wang, Yongquan Chen · 2024
Read Efficacy and safety of 4‐hydroxy 2‐methyl‐N‐(5‐methyl‐2‐thiazolyl)‐2H‐1, 2‐benzothiazin‐3‐carboxamide 1,1‐dioxide, a fast‐acting meloxicam formulation, on moderate‐to‐severe pain following abdominal surgery: A phase III randomized controlled trial by Xiaohua Liu, Yanhua Zhao, Mengchang Yang, Jinghua Ren, Wen Ouyang, Saiying Wang, Yufei Shen, Yuanli Gao, Ling Zhao, Zhong Qin, Jun Cao, Jiangyan Xia, Hongmei Zhou, Haihua Zeng, Jiangang Li, Qiongcan Li, Haitao Jiang, Ruiren Zhou, Kaiming Yuan, Shu’an Jin, Xuanqiang Zhang, Chunhui Wang, Yongquan Chen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11632392.txt.
Description
Xiaohua Liu and co-authors ran a large trial of a fast-acting pain drug for after abdominal surgery, in a 2024 study. The drug, QP001, is a long-lasting form of meloxicam, a known pain reliever. The phase three trial ran at twenty-three centers and enrolled patients facing moderate to severe pain after surgery. By chance, two patients got the drug for each one who got a dummy shot.
In all, 258 patients entered the draw and 255 took at least one dose. Pain scores were tracked hour by hour over the first day after waking. Side effects and drug reactions were logged beside the pain scores. The trial tests whether the long form eases pain well while staying safe.
Catalog record
| CREATOR | Xiaohua Liu, Yanhua Zhao, Mengchang Yang, Jinghua Ren, Wen Ouyang, Saiying Wang, Yufei Shen, Yuanli Gao, Ling Zhao, Zhong Qin, Jun Cao, Jiangyan Xia, Hongmei Zhou, Haihua Zeng, Jiangang Li, Qiongcan Li, Haitao Jiang, Ruiren Zhou, Kaiming Yuan, Shu’an Jin, Xuanqiang Zhang, Chunhui Wang, Yongquan Chen |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |