c-MET and the immunological landscape of cancer: novel therapeutic strategies for enhanced anti-tumor immunity
Parham Jabbarzadeh Kaboli, Ghazaal Roozitalab, Reyhaneh Farghadani, Zoya Eskandarian, Abdessamad Zerrouqi · 2024
Read c-MET and the immunological landscape of cancer: novel therapeutic strategies for enhanced anti-tumor immunity by Parham Jabbarzadeh Kaboli, Ghazaal Roozitalab, Reyhaneh Farghadani, Zoya Eskandarian, Abdessamad Zerrouqi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11632105.txt.
Description
Parham Jabbarzadeh Kaboli and co-authors review a growth signal receptor as a target to boost immune attack on cancer. Their review from 2024 deals with c-MET, a receptor found in many solid tumors of lung, breast, and liver. Its partner signal is made by support cells around the tumor.
When the path is switched on, it reshapes energy use in both tumor cells and a suppressor immune cell type. Key amino acids are drained from the tumor setting, which starves the immune cells that kill cancer. The review traces how blocking the receptor changes neutrophils, macrophages, T cells, and natural killer cells. It weighs pairing such blocks with immune therapy to lift results.
Catalog record
| CREATOR | Parham Jabbarzadeh Kaboli, Ghazaal Roozitalab, Reyhaneh Farghadani, Zoya Eskandarian, Abdessamad Zerrouqi |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 113 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |