Prescribing Trends of Fixed-Dose Combination Antibiotics Not Recommended by the WHO (FNRs) for ICU Patients in Six Major Areas of China During a Seven-Year Period
Liujun Zhou, Yuhua Zhao, Jianping Zhu, Jieqiong Liu, Gang Liang, Yi Yang, Gang Han, Zhenwei Yu · 2024
Read Prescribing Trends of Fixed-Dose Combination Antibiotics Not Recommended by the WHO (FNRs) for ICU Patients in Six Major Areas of China During a Seven-Year Period by Liujun Zhou, Yuhua Zhao, Jianping Zhu, Jieqiong Liu, Gang Liang, Yi Yang, Gang Han, Zhenwei Yu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11632048.txt.
Description
Liujun Zhou and seven co-authors track prescriptions of antibiotic combinations that the World Health Organization does not recommend, in a 2024 study. Fixed-dose combinations pack two antibiotics in one pill, and unapproved mixes can fuel drug resistance. The team mined prescription records for intensive care patients in six major areas of China from 2013 to 2019. Over fifteen million prescriptions were screened, covering nearly one and a half million patients.
About six percent of patients received a non-recommended combination at least once. The yearly count of such patients rose over the period, even as their share shifted. Trends were also broken down by drug and by hospital. The numbers give regulators a baseline for curbing products that add resistance risk without proven benefit.
Catalog record
| CREATOR | Liujun Zhou, Yuhua Zhao, Jianping Zhu, Jieqiong Liu, Gang Liang, Yi Yang, Gang Han, Zhenwei Yu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |