MMP9: Link between neuropathy and colorectal cancer?
Cynthia Rosa Regalado, Mihály Balogh · 2024
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Description
Cynthia Regalado and Mihály Balogh review a possible shared culprit in colon cancer and nerve pain in a 2024 paper. Chemotherapy remains a main treatment for colorectal cancer, yet about three in ten patients end up with lasting nerve damage and pain that no drug relieves well.
The review weighs the role of MMP9, an enzyme that cuts proteins and shapes tissue growth. MMP9 helps colorectal tumors spread, and it also shows up in the nerve damage that chemo leaves behind. Drawing on twenty years of studies, the authors trace how the same pathways may drive both harms. If MMP9 truly links them, blocking it could open a new treatment path.
Catalog record
| CREATOR | Cynthia Rosa Regalado, Mihály Balogh |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 63 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |