A rare case of complicated typhoid fever presenting with secondary Hemophagocytic Lymphohistiocytosis
Mir Wasim Ali, Soumadip Rakshit, Atreyee Sarkar, Md Karimulla Mondal, Anup Kumar Datta, Uttara Chatterjee · 2024
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Description
Mir Wasim Ali and co-authors report a typhoid case that spun into a rare immune storm. Their patient, a 24-year-old man from north-eastern India, arrived with spiking fever, confused behavior, a widespread rash, and bleeding from the gut. Typhoid fever, caused by Salmonella Typhi, usually stays a simpler febrile illness, though it can bleed or pierce the bowel.
Tests of his bone marrow showed blood cells being devoured by their own kind, the mark of hemophagocytic lymphohistiocytosis. In this syndrome the immune system over-fires and attacks the body it should defend. It is a seldom-seen partner of typhoid. The authors share the case to warn tropical fever teams that this storm can hide behind a common infection.
Catalog record
| CREATOR | Mir Wasim Ali, Soumadip Rakshit, Atreyee Sarkar, Md Karimulla Mondal, Anup Kumar Datta, Uttara Chatterjee |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |