A case of disseminated nocardia infection with initial symptoms manifesting as cognitive impairment: Case report and literature review

Xiayahu Li, Weiguo Zhou, Kai Zhao, Yaolin Li · 2024

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Description

Xiayahu Li and three co-authors describe a rare bacterial infection that first showed up as confusion, in this 2024 case report with a literature review. Nocardia bacteria live in soil and can spread through the body, including to the brain, where they are hard to spot and deadly if missed.

Their patient, a 58-year-old man with lung disease, kidney inflammation, and steroid-driven diabetes, arrived with garbled speech, fever, cough, breathlessness, and mental symptoms. Scans showed severe pneumonia and lung damage. Gene sequencing of samples named the culprit, Nocardia farcinica, after a first antibiotic failed. A tailored three-drug regimen brought early improvement, but the patient left the hospital early over costs and later died. The authors stress fast molecular testing, prompt matched therapy, and the real-world barriers, like money, that can undo both.

Catalog record

CREATORXiayahu Li, Weiguo Zhou, Kai Zhao, Yaolin Li
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE25 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11630925

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