AnnoGCD: a generalized category discovery framework for automatic cell type annotation

Francesco Ceccarelli, Pietro Liò, Sean B Holden · 2024

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Description

Francesco Ceccarelli and co-authors present AnnoGCD, a tool that labels cell types in single cell gene data, in a 2024 paper. Hand labeled training sets are costly, and new cell types keep turning up. A tool that only knows fixed labels misses them.

AnnoGCD mixes a small labeled set with raw data. A first block sorts the known types, and a second block hunts for new clusters on its own. Tests ran on five human data sets and a mouse atlas. The tool beat rivals on both known and new types, and it held up when some types were rare. Code and data are posted in public.

Catalog record

CREATORFrancesco Ceccarelli, Pietro Liò, Sean B Holden
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11629990

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