Application of a new type of double-lumen endotracheal tube in preterm infants with respiratory distress syndrome: study protocol for a non-inferiority randomised controlled trial (NISA)
Jin Gao, Hanmei Xiong, Panrong Nie, Hong Yang, Dan Li, Xingmei Deng, Yuan Shi, Chuanfeng Li, Weihong Yu, Jie Yang, Yuxuan Du · 2024
Read Application of a new type of double-lumen endotracheal tube in preterm infants with respiratory distress syndrome: study protocol for a non-inferiority randomised controlled trial (NISA) by Jin Gao, Hanmei Xiong, Panrong Nie, Hong Yang, Dan Li, Xingmei Deng, Yuan Shi, Chuanfeng Li, Weihong Yu, Jie Yang, Yuxuan Du (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11628960.txt.
Description
Babies born early often struggle to breathe because their lungs lack a slippery coating called surfactant. Jin Gao and co-authors describe a trial protocol in 2024 testing a new breathing tube with a thin side channel for giving that coating. The tube lets doctors deliver surfactant while air support continues, a twist on a standard intubate-treat-remove method.
The trial will enroll one hundred thirty-two preterm infants across six newborn units in Yunnan, China, assigned by chance to the new tube or to a less invasive catheter method. The main outcome is the need for full mechanical ventilation within seventy-two hours of birth. Complications and later lung infections are also tracked. The team aims to show the tube is no worse, giving doctors another option.
Catalog record
| CREATOR | Jin Gao, Hanmei Xiong, Panrong Nie, Hong Yang, Dan Li, Xingmei Deng, Yuan Shi, Chuanfeng Li, Weihong Yu, Jie Yang, Yuxuan Du |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |