Cell-free placental DNA: What do we really know?
Natalie Yuen, Melanie Lemaire, Samantha L. Wilson · 2024
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Description
Yuen, Lemaire, and Wilson review what is actually known about placental DNA floating in a pregnant person's blood in this 2024 article. This cell-free placental DNA already powers noninvasive prenatal testing in clinics worldwide. It also promises a window on the placenta's genome without invasive sampling.
The review covers where the DNA comes from and what its molecular traits are. Despite wide clinical use, the basic biology behind the fragments stays poorly understood. That gap limits both research designs and new clinical uses. The authors map the open questions and suggest directions for future work. The piece serves readers who use these tests and want their foundations made clear.
Catalog record
| CREATOR | Natalie Yuen, Melanie Lemaire, Samantha L. Wilson |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |