Exploring the Connections: Autophagy, Gut Microbiota, and Inflammatory Bowel Disease Pathogenesis
Arunkumar Subramanian, Afrarahamed J, Tamilanban T, Vinoth Kumarasamy, M Yasmin Begum, Mahendran Sekar, Vetriselvan Subramaniyan, Ling Shing Wong, Adel Al Fatease · 2024
Read Exploring the Connections: Autophagy, Gut Microbiota, and Inflammatory Bowel Disease Pathogenesis by Arunkumar Subramanian, Afrarahamed J, Tamilanban T, Vinoth Kumarasamy, M Yasmin Begum, Mahendran Sekar, Vetriselvan Subramaniyan, Ling Shing Wong, Adel Al Fatease (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11626960.txt.
Description
Arunkumar Subramanian and co-authors review how three things — gut microbes, the cell's recycling system, and immune activity — combine in inflammatory bowel disease. The disease group covers Crohn's disease and ulcerative colitis, long-term gut conditions whose causes are tangled. Microbe imbalance in the gut is linked to the disease, and the recycling process, called autophagy, keeps gut tissue steady and calms immune responses.
When recycling falters and microbes fall out of balance at the same time, the review argues, inflammation grows worse than either fault alone would cause. The authors also trace how diet shifts the microbes and, through them, the disease. They close by weighing treatments that retune the microbes or the recycling pathways, and the promise of care tailored to each patient.
Catalog record
| CREATOR | Arunkumar Subramanian, Afrarahamed J, Tamilanban T, Vinoth Kumarasamy, M Yasmin Begum, Mahendran Sekar, Vetriselvan Subramaniyan, Ling Shing Wong, Adel Al Fatease |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |