Genetic characterization and clonal analysis of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae from canine and human origins

Nwai Oo Khine, Asad Ali Shah, Tanittha Chatsuwan, Jitrapa Yindee, Natthapong Supimon, Imporn Saenkankam, David John Hampson, Nuvee Prapasarakul · 2024

Read Genetic characterization and clonal analysis of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae from canine and human origins by Nwai Oo Khine, Asad Ali Shah, Tanittha Chatsuwan, Jitrapa Yindee, Natthapong Supimon, Imporn Saenkankam, David John Hampson, Nuvee Prapasarakul (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11626800.txt.

Description

Bacteria that defeat carbapenems, the antibiotics of last resort, turn up in dogs as well as people, raising fears of germs hopping between pets and owners. Nwai Oo Khine and co-authors compared such bacteria from Bangkok dogs and patients in 2024, sequencing fifty-two resistant isolates. The same successful strain type appeared in both hosts, and resistance plasmids overlapped.

Yet fine-grained family trees showed no clone shared between dog and human isolates: each host seems to acquire the bacteria independently. The authors say the overlap in types still warns that cross-species spread is possible under the right conditions, and they urge joint monitoring of animals and people.

Catalog record

CREATORNwai Oo Khine, Asad Ali Shah, Tanittha Chatsuwan, Jitrapa Yindee, Natthapong Supimon, Imporn Saenkankam, David John Hampson, Nuvee Prapasarakul
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11626800

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