Compartmentalized pooling generates orientation selectivity in wide-field amacrine cells
Wanyu Lei, Damon A. Clark, Jonathan B. Demb · 2024
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Description
Wanyu Lei, Damon Clark, and Jonathan Demb study how mouse retina cells pick out line tilt in 2024. Giant wide-field cells in the inner retina show tilt-tuned calcium marks along long straight arms. Each arm acts as its own sealed unit, with a long but bounded field the team calls compartmentalized pooling.
Field models show that pooling alone makes tilt choice, while a center-surround clash shapes pitch tuning. Crossed signals from the other light pole are not needed for tilt. A lean cell model copies the pooling from feed-in plus a sharp rise in membrane hold between body and arm.
Catalog record
| CREATOR | Wanyu Lei, Damon A. Clark, Jonathan B. Demb |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |